Coverage Policies

Important! Please note:

Current policies effective through April 30, 2024.

Use the index below to search for coverage information on specific medical conditions.

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QualChoice reserves the right to alter, amend, change or supplement medical policies as needed. QualChoice reviews and authorizes services and substances. CPT and HCPCS codes are listed as a convenience and any absent, new or changed codes do not alter the intent of the policy.

INDEX:
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Effective Date: 01/01/2024 Title: Aphexda
Revision Date: Document: BI728:00
CPT Code(s):
Public Statement

Effective Date:

a)    This policy will apply to all services performed on or after the above revision date which will become the new effective date.

b)    For all services referred to in this policy that were performed before the revision date, contact customer service for the rules that would apply.

1)    Aphexda (motixafortide) requires prior authorization.

2)    Aphexda is used to mobilize hematopoietic stem cells in combination with filgrastim.


Medical Statement

Initial Approval Criteria

I.             Mobilization of Hematopoietic Stem Cell (must meet all):

a.    Diagnosis of Multiple Myeloma (MM);

b.    Prescribed by or in consultation with an oncologist or hematologist;

c.    Age > 18 years:

d.    Prescribed in combination with a formulary G-CSF

e.    Member is scheduled to receive autologous stem cell transplantation;

f.     Dose is consistent with FDA-labeling

 

Approval Duration: 3 months

 

Reauthorization Requests must meet initial approval criteria.


Reference

1.    Aphexda Prescribing Information. Waltham, MA: BioLineRx; September 2023. Available at: www.aphexda.com. Accessed September 13, 2023.

2.    National Comprehensive Cancer Network Drugs and Biologics Compendium. Available at: https://www.nccn.org/professionals/drug_compendium/content/. Accessed September 29, 2023.

3.    National Comprehensive Cancer Network. Multiple Myeloma Version 1.2024. Available at: https://www.nccn.org/professionals/physician_gls/pdf/myeloma.pdf. Accessed September 29, 2023.

4.    National Comprehensive Cancer Network. Hematopoietic Cell Transplantation Version 2.2023. Available at: https://www.nccn.org/professionals/physician_gls/pdf/hct.pdf. Accessed September 29, 2023.

 


Application to Products
This policy applies to all health plans administered by QualChoice, both those insured by QualChoice and those that are self-funded by the sponsoring employer, unless there is indication in this policy otherwise or a stated exclusion in your medical plan booklet. Consult the individual plan sponsor Summary Plan Description (SPD) for self-insured plans or the specific Evidence of Coverage (EOC) for those plans insured by QualChoice. In the event of a discrepancy between this policy and a self-insured customer’s SPD or the specific QualChoice EOC, the SPD or EOC, as applicable, will prevail. State and federal mandates will be followed as they apply.
Changes: QualChoice reserves the right to alter, amend, change or supplement benefit interpretations as needed.
This policy has recently been updated. Please use the index above or enter policy title in search bar for the latest version.