Effective Date:

a)    This policy will apply to all services performed on or after the above Revision date which will become the new effective date.

b)    For all services referred to in this policy that were performed before the revision date, contact customer service for the rules that would apply.

Periodic urine drug screening may be useful in monitoring pain therapy compliance.  Screening is also appropriate in pregnancy or prior to performing Multiple Sleep Latency Testing. In these circumstances, a simple screening test is appropriate and is covered.  Mandated drug screening or testing for work or legal purposes is not covered.  Definitive testing is not covered at out-of-network labs.

This policy does not limit the use of drug screening in emergency or inpatient care. 

1)    Urine screening for drugs of abuse in the outpatient setting will be considered medically necessary when the result will influence medical care, such as in: 

                                  i.    Pregnancy, or

                                ii.    Patients taking narcotic pain medications on a chronic basis, or

                               iii.    Prior to performing a Multiple Sleep Latency Test. 

2)    A multiplex drug screen either performed in the physician’s office or in a laboratory, is the appropriate test in these circumstances. Presumptive drug screening (80305 or 80306) are the only tests that will be covered when billed by the physician’s office, and will be covered only once per day, and upto 2 per month and 24 per 12 months. CPT codes adequately describe these tests, therefore HCPCS codes will not be accepted. Any other drug testing, whether presumptive or definitive, billed by the physician’s office, will be denied, provider liability, as inappropriately coded.

3)    Presumptive testing (80307) by a laboratory, ER or inpatient facility or definitive testing (80320 - 80377) is limited to once per day. Standard CPT codes adequately describe these tests, therefore temporary CPT codes or HCPCS codes will not be accepted. 

4)    Definitive testing is appropriate when a preceding drug screen is positive, and will be considered medically necessary for those drugs with a positive screening test. If initial screening performed has negative findings for a specific drug, additional testing for that drug on same day will be denied as not medically necessary. Definitive testing may also be appropriate for drugs that have been prescribed for the patient but are not included in the available presumptive test. Confirmatory testing will be covered only when billed by a facility laboratory or an independent in-network laboratory. Out-of-network laboratories are not covered for this type of testing.

Codes Used In This BI:

HCPCS codes G0480 - G0483 and temporary CPT codes 0006U, 0007U, 0011U, 0020U, 0093U, 0116U and 0017U are not covered. The procedures these codes are used for are considered to be adequately described by standard CPT codes.

Standards of Practice Committee of the American Academy of Sleep Medicine.  Practice parameters for Clinical Use of the Multiple Sleep Latency Test and the Maintenance of Wakefulness Test.  Sleep 2005; 28(1):113-121

2. American College of Occupational and Environmental Medicine.  Chronic pain.  In: Occupational medicine practice guidelines; 2008: 73-502.

3. Colorado Division of Worker’s Compensation.  Chronic pain disorder medical treatment guidelines.  2011 Dec 27.

4. Management of Opioid Therapy for Chronic Pain Working Group.  VA/DoD clinical practice guideline for management of opioid therapy for chronic pain.  2010 May.

Addendum:

1.    Effective 01/01/2017: the AMA CPT classification no longer distinguishes between Class A and Class B drugs. The 2017 AMA CPT classification distinguishes between simple optical screening tests which are commonly performed in a CLIA waived office lab and instrument chemistry analyzers that are more typically seen in a commercial laboratory.  While presumptive drug screening can be performed either way, definitive or confirmatory testing is best done by a commercial laboratory with instrument chemistry analyzers. Updated with 2017 CPT codes.  Noted deletion of the following HCPCS codes, effective 1/1/17: G0477 – G0479. Updated with new codes.

2.    Effective 01/01/2018: Testing for drugs of abuse (80307 - 80377) will not be covered at out-of-network (OON) labs.

3.    Effective 10/01/2018: Aligned quantity limits with standard (once daily) NCCI edits.

4.    Effective 07/01/2019: Added new code (0093U).

5.    Effective 10/01/2019: Added new temporary CPT codes.

6.    Effective 09/01/2020: presumptive drug testing (CPT 80305-80306) is covered not more than once per day, or 2 per month and 24 per 12 months. Confirmatory drug testing is also covered once per day and up to twice a month and 24 per 12 months.

7.    Effective 01/01/2021: Added new code 0227U, as noncovered. CPT 82077 is considered experimental and investigational and is not covered.

8.    Effective 05/01/2021: drug testing (CPT 80305 to 80377) are cumulatively covered for not more than once per day, or 2 per month and 24 per 12 months.

Resource Document:

BI345 Testing for Drugs of Abuse RD