Effective Date:12/01/2011 |
Title:Magnetoenchalopgraphy (MEG)
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Revision Date:10/01/2015
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Document:BI329:00
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CPT Code(s):95965-95967, S8035
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Public Statement
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Effective Date:
a)
This policy
will apply to all services performed on or after the above revision date which
will become the new effective date.
b)
For all
services referred to in this policy that were performed before the revision
date, contact customer service for the rules that would apply.
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Magnetoencephalography is a
noninvasive functional imaging technique which records the weak magnetic
forces associated with the brain’s electrical activity.
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This sophisticated technique is
sometimes helpful in localizing brain function in patients preparing to
undergo brain surgery for intractable epilepsy.
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This technology is covered in
patients who meet the medical policy criteria for intractable epilepsy.
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Medical Statement
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Magnetic
source imaging (MSI) or magnetoencephalography (MEG) are considered
medically necessary for pre-surgical evaluation in persons with intractable
focal epilepsy to identify and localize areas of epileptiform activity, when
discordance or continuing questions arise from among other techniques
designed to localize a focus.
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MSI or MEG is considered
experimental and investigational when used as a stand-alone test or as the
first order of test after clinical and routine electroencephalographic (EEG)
diagnosis of epilepsy.
Codes Used In This BI:
95965 Magnetoencephalography (MEG), recording and analysis;
for spontaneous brain magnetic activity (e.g., epileptic cerebral cortex
localization)
95966 Magnetoencephalography (MEG), recording and analysis; for evoked magnetic
fields, single modality (e.g., sensory, motor, language, or visual cortex
localization)
95967 Magnetoencephalography (MEG), recording and analysis; for evoked magnetic
fields, each additional modality (e.g., sensory, motor, language, or visual
cortex localization) (List separately in addition to code for primary procedure)
S8035 Magnetic source imaging
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Limits
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1.
MSI or MEG is
considered experimental and investigational for the following indications (not
an all inclusive list):
·
Evaluation of
Alzheimer`s disease
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Evaluation of
autism
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Evaluation of
brain tumors
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Evaluation of
cognitive and mental disorders
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Evaluation of
developmental dyslexia
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Evaluation of
multiple sclerosis
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Evaluation of
Parkinson`s disease
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Evaluation of
schizophrenia
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Evaluation of
stroke rehabilitation
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Evaluation of
traumatic brain injury
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Fetal
neurological assessment.
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Reference
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Blumenfeld LD, Clementz BA.
Response to the first stimulus determines reduced auditory evoked response
suppression in schizophrenia: Single trials analysis using MEG. Clin
Neurophysiol. 2001; 112(9):1650-1659.
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Zappasodi F, Tecchio F, Pizzella
V, et al. Detection of fetal auditory evoked responses by means of
magnetoencephalography. Brain Res. 2001; 917(2):167-173.
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Rosenow F, Luders H. Presurgical
evaluation of epilepsy. Brain. 2001; 124(Pt 9):1683-1700.
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Filipek PA, Accardo PJ, Ashwal S,
et al. American Academy of Neurology. Practice parameter: Screening and
diagnosis of autism. Report of the Quality Standards Subcommittee of the
American Academy of Neurology and the Child Neurology Society. Neurology.
2000; 55(4):468-479.
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Kuzniecky RI, Knowlton RC.
Neuroimaging of epilepsy. Semin Neurol. 2002; 22(3):279-288.
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Feichtinger M, Holl A, Korner E,
Schrottner O, et al. Future aspects of the presurgical evaluation in
epilepsy. Acta Neurochir Suppl. 2002; 84:17-26.
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Barkley GL. Controversies in
neurophysiology. MEG is superior to EEG in localization of interictal
epileptiform activity: Pro. Clin Neurophysiol. 2004; 115(5):1001-1009.
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Baumgartner C. Controversies in
clinical neurophysiology. MEG is superior to EEG in the localization of
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115(5):1010-1020.
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Knowlton RC, Shih J.
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Parra J, Kalitzin SN, da Silva
FH. Magnetoencephalography: An investigational tool or a routine clinical
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Billingsley-Marshall RL, Simos
PG, Papanicolaou AC. Reliability and validity of functional neuroimaging
techniques for identifying language-critical areas in children and adults.
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Stefan H, Hummel C, Scheler G, et
al. Magnetic brain source imaging of focal epileptic activity: A synopsis of
455 cases. Brain. 2003;126(Pt 11):2396-2405.
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Lopes da Silva FH. What is
magnetoencephalography and why it is relevant to neurosurgery? Adv Tech
Stand Neurosurg. 2005;30:51-67.
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Pataraia E, Lindinger G, Deecke
L, et al. Combined MEG/EEG analysis of the interictal spike complex in
mesial temporal lobe epilepsy. Neuroimage. 2005;24(3):607-614.
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Papanicolaou AC, Pataraia E,
Billingsley-Marshall R, et al. Toward the substitution of invasive
electroencephalography in epilepsy surgery. J Clin Neurophysiol.
2005;22(4):231-237.
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Wirrell E, Whiting S, Farrell K.
Management of intractable epilepsy in infancy and childhood. Adv Neurol.
2006;97:463-491.
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Knowlton RC, Elgavish R, Howell
J, et al. Magnetic source imaging versus intracranial electroencephalogram
in epilepsy surgery: A prospective study. Ann Neurol. 2006;59(5):835-842.
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Criado JR, Amo C, Quint P, et al.
Using magnetoencephalography to study patterns of brain magnetic activity in
Alzheimer`s disease. Am J Alzheimers Dis Other Demen. 2006;21(6):416-423.
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Ontario Ministry of Health,
Medical Advisory Secretariat (MAS). Functional brain imaging. Health
Technology Policy Assessment. Toronto, ON: MAS; December 2006. Available at:
http://www.health.gov.on.ca/english/providers/program/mas/tech/reviews/pdf/
rev_fbi_012507.pdf. Accessed April 3, 2007.
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Rampp S, Stefan H.
Magnetoencephalography in presurgical epilepsy diagnosis. Expert Rev Med
Devices. 2007;4(3):335-347.
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Poza J, Hornero R, Abásolo D, et
al. Evaluation of spectral ratio measures from spontaneous MEG recordings in
patients with Alzheimer`s disease. Comput Methods Programs Biomed.
2008;90(2):137-147.
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Lau M, Yam D, Burneo JG. A
systematic review on MEG and its use in the presurgical evaluation of
localization-related epilepsy. Epilepsy Res. 2008;79(2-3):97-104.
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Leijten FS, Huiskamp G.
Interictal electromagnetic source imaging in focal epilepsy: Practices,
results and recommendations. Curr Opin Neurol. 2008;21(4):437-445.
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Korvenoja A, Kirveskari E, Aronen
HJ, et al. Sensorimotor cortex localization: Comparison of
magnetoencephalography, functional MR imaging, and intraoperative cortical
mapping. Radiology. 2006;241(1):213-222.
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Grover KM, Bowyer SM, Rock J, et
al. Retrospective review of MEG visual evoked hemifield responses prior to
resection of temporo-parieto-occipital lesions. J Neurooncol.
2006;77(2):161-166.
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Pelletier I, Sauerwein HC, Lepore
F, et al. Non-invasive alternatives to the Wada test in the presurgical
evaluation of language and memory functions in epilepsy patients. Epileptic
Disord. 2007;9(2):111-126.
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Sutherling WW, Mamelak AN,
Thyerlei D, et al. Influence of magnetic source imaging for planning
intracranial EEG in epilepsy. Neurology. 2008;71(13):990-996.
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Knowlton RC, Elgavish RA, Limdi
N, et al. Functional imaging: I. Relative predictive value of intracranial
electroencephalography. Ann Neurol. 2008;64(1):25-34.
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Knowlton RC, Elgavish RA,
Bartolucci A, et al. Functional imaging: II. Prediction of epilepsy surgery
outcome. Ann Neurol. 2008;64(1):35-41.
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Knowlton RC. Can
magnetoencephalography aid epilepsy surgery? Epilepsy Curr. 2008;8(1):1-5.
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American Academy of Neurology
Professional Association (AANPA). Magnetoencephalography (MEG) Policy.
Recommended by the AANPA Medical Economics and Management Committee.
Approved by the AANPA Board of Directors on May 8, 2009. St. Paul, MN: AANPA;
2009.
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Bagic A, Funke ME, Ebersole J;
ACMEGS Position Statement Committee. American Clinical MEG Society (ACMEGS)
position statement: The value of magnetoencephalography (MEG)/magnetic
source imaging (MSI) in noninvasive presurgical evaluation of patients with
medically intractable localization-related epilepsy. J Clin Neurophysiol.
2009;26(4):290-293.
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Cimon K, Spry C.
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effectiveness. Health Technology Inquiry Service (HTIS). Ottawa, ON:
Canadian Agency for Drugs and Technologies in Health (CADTH); September 2,
2009.
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Clark M, Spry C.
Magnetoencephalography for neurocognitive disorders: Clinical effectiveness.
Health Technology Inquiry Service (HTIS). Ottawa, ON: Canadian Agency for
Drugs and Technologies in Health (CADTH); September 2, 2009.
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Funke M, Constantino T, Van Orman
C, Rodin E. Magnetoencephalography and magnetic source imaging in epilepsy.
Clin EEG Neurosci. 2009;40(4):271-280.
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Lowery CL, Govindan RB, Preissl
H, et al. Fetal neurological assessment using noninvasive
magnetoencephalography. Clin Perinatol. 2009;36(3):701-709.
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Stam CJ. Use of
magnetoencephalography (MEG) to study functional brain networks in
neurodegenerative disorders. J Neurol Sci. 2010;289(1-2):128-134.
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Siekmeier PJ, Stufflebeam SM.
Patterns of spontaneous magnetoencephalographic activity in patients with
schizophrenia. J Clin Neurophysiol. 2010;27(3):179-190.
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Haddad N, Govindan RB, Vairavan
S, et al. Correlation between fetal brain activity patterns and behavioral
states: An exploratory fetal magnetoencephalography study. Exp Neurol. 2011
Jan 13. [Epub ahead of print]
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Application to Products
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This policy applies to all health plans administered by QualChoice, both those insured by QualChoice and those that are self-funded by the sponsoring employer, unless there is indication in this policy otherwise or a stated exclusion in your medical plan booklet. Consult the individual plan sponsor Summary Plan Description (SPD) for self-insured plans or the specific Evidence of Coverage (EOC) for those plans insured by QualChoice. In the event of a discrepancy between this policy and a self-insured customer’s SPD or the specific QualChoice EOC, the SPD or EOC, as applicable, will prevail. State and federal mandates will be followed as they apply.
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Changes: QualChoice reserves the right to alter, amend, change or supplement benefit interpretations as needed.
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